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Some people who take medicines called DPP-4 inhibitors like JANUVIAmay develop joint pain that can be severeCall your doctor if you have severe joint pain.

Serious side effects can happen in people who take JANUVIAincluding pancreatitiswhich may be severe and lead to deathBefore you start taking JANUVIAtell your doctor if you’ve ever had pancreatitisStop taking JANUVIA and call your doctor right.

Some people who take medicines called DPP-4 inhibitors like JANUVIA may develop a skin reaction called bullous pemphigoid that can require treatment in a hospitalTell your doctor right away if you develop blisters or the breakdown of the outer layer of your skinerosionYour doctor may tell you to stop taking JANUVIA.

JANUVIA should not be used in patients with type 1 diabetes or with diabetic ketoacidosisincreased ketones in the blood or urineIf you have had pancreatitisinflammation of the pancreasit is not known if you have a higher chance of getting it while taking JANUVIA.

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