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Occurrence of galactorrheaCertain medications like tranquilizersdrugs for high pressureand antidepressants can result in lactation without pregnancyCommon medications associated with galactorrhea include agents to block dopamine and histamine receptors and dopamine-depleting agentsBirth control pills can also induce lactationThis is because the estrogen in these pills suppresses the hypothalamic secretion of the prolactin inhibitory factor and stimulates lactotrophsIn such casesconsult a doctor immediatelyPituitary tumorsThe most common cause of galactorrhea is a tumor in the pituitary glandBenign tumors like prolactinoma result in the production of prolactinToo much prolactin in the blood causes the stimulation of milk by the mammary glands along with other symptoms like tenderness in the breastsheadachedecreased sexual activityinfertility and irregular menstruationThese non-cancerous tumors can affect men as well and result in decreased sexual driveimpotence and enlargement of the breast tissuesHypothyroidismIt is a rare cause of galactorrhea butprimary hypothyroidism can lead to an increase in the production of the thyrotropin-releasing hormoneThis leads to the release of excess prolactin and lactationHyperprolactinemiaexcess of prolactincan also cause a drop in the metabolic clearance of prolactin and a decrease in the secretion of dopamineChronic renal failureIn certain rare casespeople with chronic kidney disease have high levels of prolactin due to the inability of the kidneys to clear the prolactinThis can also lead to discharge from the nipples.
Cabgolin is contraindicated in patients with uncontrolled hypertension or known hypersensitivity to ergot derivatives ergotamineergonovineergomarcafergotdihydroergotaminemigranal nasal sprayd.
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