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DUse in LIFE-THREATENING emergencies when no safer drug availablePositive evidence of human fetal risk.

Patients with long-term kidney disease cannot eliminate phosphate from their bodiesThis leads to hyperphosphataemiawhichin the long termcan cause complications such as heart and bone diseaseThe active substance in Renagelsevelamer hydrochlorideis a phosphate binderWhen taken with mealsit attaches to phosphate from food within the gutpreventing it from being absorbed into the bodyThis helps to reduce the phosphate levels in the blood.

In interaction studies in healthy volunteersRenagel had no effect on the bioavailability of digoxinwarfarinenalapril or metoprolol.

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another major driver of renagel s growth will be its potential to improve patient morbidity and mortality.